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KMID : 0605620070140010048
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Journal of Korean Society of Biological Psychiatry
2007 Volume.14 No. 1 p.48 ~ p.54
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Relationship between Behavioral and Psychological Symptoms and Patient and Caregiver Quality of Life in Alzheimer’s Disease
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Kim Sung-Wan
Shin Il-Seon
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Abstract
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Objectives: This study aimed to examine the relationship between behavioral and psychological symptoms of dementia(BPSD) and patient and caregiver QOL in Alzheimer’s disease(AD).
Methods: Fifty-one AD patients and their caregivers participated. Measures about patients were Neuropsychiatric Inventory(NPI), Korean version of QOL-Alzheimer’s Disease(KQOL-AD), Activities of Daily Living(ADL), Clinical Dementia Rating(CDR), and Korean version-Mini Mental State Examination(K-MMSE). Caregiver QOL was assessed with KQOL-AD and General Health Questionnaire/Quality of Life-12(GHQ/ QOL-12).
Results : Patient QOL-AD on patient ratings was negatively correlated with appetite/eating change and NPI scores. Patient QOL-AD on caregiver ratings was negatively correlated with hallucinations, depression/dysphoria, and NPI scores. Caregiver QOL assessed by the GHQ/QOL-12 was negatively correlated with agitation/aggression, depression/dysphoria, and NPI scores and was negatively correlated with distress related to agitation/aggression, depression/dysphoria, and NPI scores.
Conclusion: BPSD of AD patients was associated with low QOL of both patients and caregivers. Thus, interventions of BPSD were needed to improve both patient and caregiver QOL.
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KEYWORD
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Alzheimer’s disease, Behavioral and psychological symptoms, Quality of life, Caregiver
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